Glucosamine: A Supplement That May Ease Your Joint Pain

If you’re looking for a supplement that may ease your joint pain, glucosamine might be worth a try. Some studies show it gives relief for mild to moderate knee osteoarthritis, and it may work for other joints, too.

What Is It?

Glucosamine is a natural chemical compound in your body. But it also comes in the form of a supplement. There are two main types: hydrochloride and sulfate.

What Does It Do?

The glucosamine in your body helps keep up the health of your cartilage — the rubbery tissue that cushions bones at your joints. But as you get older, your levels of this compound begin to drop, which leads to the gradual breakdown of the joint.There’s some evidence that glucosamine sulfate supplements help counteract this effect, although experts aren’t sure how.Some people have also used glucosamine to try to treat rheumatoid arthritis and other conditions, such as inflammatory bowel disease, asthma, allergies, chronic venous insufficiency, sports injuries, temporomandibular joint problems (TMJ), and long-term low back pain. So far, though, there’s not much scientific evidence that it works for those problems.